Eplerenone suppresses aldosterone/ salt-induced expression of NOX-4

Introduction: Salt-induced hypertension in the Dahl rat is associated with increases in angiotensin II, aldosterone, free radical generation and endothelial dysfunction. However, little is known about the specific mechanism(s) associated with the end-organ damage effects of aldosterone. We hypothesi...

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Bibliographic Details
Main Authors: Mohamed A Bayorh, Aisha Rollins-Hairston, Jeffery Adiyiah, Deborah Lyn, Danita Eatman
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2011-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320310391330