Eplerenone suppresses aldosterone/ salt-induced expression of NOX-4
Introduction: Salt-induced hypertension in the Dahl rat is associated with increases in angiotensin II, aldosterone, free radical generation and endothelial dysfunction. However, little is known about the specific mechanism(s) associated with the end-organ damage effects of aldosterone. We hypothesi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2011-09-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.1177/1470320310391330 |