Rapid in vitro derivation of endothelium directly from human cancer cells.

The development of an independent blood supply by a tumor is essential for maintaining growth beyond a certain limited size and for providing a portal for metastatic dissemination. Host-derived endothelial cells (ECs) residing in and compromising the tumor vasculature originate via distinct processe...

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Bibliographic Details
Main Authors: Jennifer D Elster, Terence F McGuire, Jie Lu, Edward V Prochownik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3793940?pdf=render