The Hedgehog signal transducer Smoothened and microRNA-326: pathogenesis and regulation of drug resistance in pediatric B-cell acute lymphoblastic leukemia

The Hedgehog signal transducer Smoothened and microRNA-326: pathogenesis and regulation of drug resistance in pediatric B-cell acute lymphoblastic leukemia

Zahra Sheybani, Soheila Rahgozar, Elaheh Sadat GhodousiDepartment of Biology, Faculty of Science, University of Isfahan, Isfahan, IranPurpose: Multidrug resistance (MDR) and the subsequent disease relapse are the major causes of childhood acute lymphoblastic leukemia (ALL) related death. The Hedgeho...

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Bibliographic Details
Main Authors: Sheybani Z, Rahgozar S, Ghodousi ES
Format: Article
Language:English
Published: Dove Medical Press 2019-08-01
Series:Cancer Management and Research
Subjects:
Hh pathway
Smo
miR-326
ABC transporters
Online Access:https://www.dovepress.com/the-hedgehog-signal-transducer-smoothened-and-microrna-326-pathogenesi-peer-reviewed-article-CMAR

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https://www.dovepress.com/the-hedgehog-signal-transducer-smoothened-and-microrna-326-pathogenesi-peer-reviewed-article-CMAR

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