Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination.

Clostridium difficile is a Gram-positive spore-forming pathogen and a leading cause of nosocomial diarrhea. C. difficile infections are transmitted when ingested spores germinate in the gastrointestinal tract and transform into vegetative cells. Germination begins when the germinant receptor CspC de...

Full description

Bibliographic Details
Main Authors: Kelly A Fimlaid, Owen Jensen, M Lauren Donnelly, Michael B Francis, Joseph A Sorg, Aimee Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005239