Cofilin-Mediated Actin Stress Response Is Maladaptive in Heat-Stressed Embryos

Summary: Environmental stress threatens the fidelity of embryonic morphogenesis. Heat, for example, is a teratogen. Yet how heat affects morphogenesis is poorly understood. Here, we identify a heat-inducible actin stress response (ASR) in Drosophila embryos that is mediated by the activation of the...

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Bibliographic Details
Main Authors: Lauren Figard, Liuliu Zheng, Natalie Biel, Zenghui Xue, Hasan Seede, Seth Coleman, Ido Golding, Anna Marie Sokac
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719302785