The Human IL-23 Decoy Receptor Inhibits T-Cells Producing IL-17 by Genetically Engineered Mesenchymal Stem Cells

The immunomodulatory and self-renewable features of human adipose mesenchymal stem cells (hAD-MSCs) mark their importance in regenerative medicine. Interleukin 23 (IL- 23) as a proinflammatory cytokine suppresses T regulatory cells (Treg) and promotes the response of T helper 17 (Th17) and T helper...

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Bibliographic Details
Main Authors: Masoumeh Rostami, Kamran Haidari, Majid Shahbazi
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2018/8213912