Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine.

Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine.

Currently there are a dozen or so of new vaccine candidates in clinical trials for prevention of tuberculosis (TB) and each formulation attempts to elicit protection by enhancement of cell-mediated immunity (CMI). In contrast, most approved vaccines against other bacterial pathogens are believed to...

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Bibliographic Details
Main Authors: Rafael Prados-Rosales, Leandro Carreño, Tingting Cheng, Caroline Blanc, Brian Weinrick, Adel Malek, Todd L Lowary, Andres Baena, Maju Joe, Yu Bai, Rainer Kalscheuer, Ana Batista-Gonzalez, Noemi A Saavedra, Leticia Sampedro, Julen Tomás, Juan Anguita, Shang-Cheng Hung, Ashish Tripathi, Jiayong Xu, Aharona Glatman-Freedman, Williams R Jacobs, John Chan, Steven A Porcelli, Jacqueline M Achkar, Arturo Casadevall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006250

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https://doi.org/10.1371/journal.ppat.1006250

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