RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

<p>Abstract</p> <p>Background</p> <p>RNA-Seq is revolutionizing the way transcript abundances are measured. A key challenge in transcript quantification from RNA-Seq data is the handling of reads that map to multiple genes or isoforms. This issue is particularly importa...

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Bibliographic Details
Main Authors: Dewey Colin N, Li Bo
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/323