Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis

Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis

Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a chronic zoonotic disease where host genetics is thought to contribute to susceptibility or resistance. One of the genes implicated is the SLC11A1 gene, that encodes for the natural resistance-associated macrophage protein 1 (NRAMP1). The...

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Bibliographic Details
Main Authors: Angela Holder, Rachel Garty, Charlotte Elder, Paula Mesnard, Celine Laquerbe, Marie-Christine Bartens, Mazdak Salavati, Muhammad Zubair Shabbir, Thomas Tzelos, Timothy Connelly, Bernardo Villarreal-Ramos, Dirk Werling
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
SLC11A1
NRAMP1
bovine tuberculosis
genetics
cattle breeds
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01420/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01420/full

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