Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication.

Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication.

DNA Polymerases generate pyrophosphate every time they catalyze a step of DNA elongation. This elongation reaction is generally believed as thermodynamically favoured by the hydrolysis of pyrophosphate, catalyzed by inorganic pyrophosphatases. However, the specific action of inorganic pyrophosphatas...

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Bibliographic Details
Main Authors: Fabio Lapenta, Alejandro Montón Silva, Renato Brandimarti, Massimiliano Lanzi, Fabio Lino Gratani, Perceval Vellosillo Gonzalez, Sofia Perticarari, Alejandro Hochkoeppler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4822814?pdf=render

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http://europepmc.org/articles/PMC4822814?pdf=render

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