A comparative study on inhibition of total astragalus saponins and astragaloside IV on TNFR1-mediated signaling pathways in arterial endothelial cells.

Both total astragalus saponins (AST) and it's main component astragaloside IV (ASIV) have been used in China as cardiovascular protective medicines. However, the anti-inflammatory activities that are beneficial for cardiovascular health have never been compared directly and the molecular mechan...

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Bibliographic Details
Main Authors: Qin-she Liu, Hai-fang Wang, An-ke Sun, Xue-ping Huo, Jin-lian Liu, Shu-hui Ma, Ning Peng, Jun Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4081628?pdf=render