Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells

<p>Abstract</p> <p>Background</p> <p>To elucidate whether rapamycin, the inhibitor of mTOR (mammalian target of rapamycin), can potentiate the cytotoxic effect of docetaxel in lung cancer cells and to probe the mechanism underlying such enhancement.</p> <p>M...

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Bibliographic Details
Main Authors: Li Hui, Wang Jiahe, Niu Huiyan, He Ping
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/28