Environmental enrichment prevents Aβ oligomer-induced synaptic dysfunction through mirna-132 and hdac3 signaling pathways

Environmental enrichment prevents Aβ oligomer-induced synaptic dysfunction through mirna-132 and hdac3 signaling pathways

As the most common cause of progressive cognitive decline in humans, Alzheimer's disease (AD) has been intensively studied, but the mechanisms underlying its profound synaptic dysfunction remain unclear. Here we confirm that exposing wild-type mice to an enriched environment (EE) facilitates si...

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Main Authors: Zhiyun Wei, Xingjun Meng, Rachid El Fatimy, Bowen Sun, Dongmei Mai, Junfang Zhang, Ramil Arora, Ailiang Zeng, Pingyi Xu, Shaogang Qu, Anna M. Krichevsky, Dennis J. Selkoe, Shaomin Li
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611930292X

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http://www.sciencedirect.com/science/article/pii/S096999611930292X

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