hnRNPK-regulated LINC00263 promotes malignant phenotypes through miR-147a/CAPN2

Abstract Malignant characteristics of cancers, represented by rapid cell proliferation and high metastatic potential, are a major cause of high cancer-related mortality. As a multifunctional RNA-binding protein, heterogeneous nuclear ribonucleoprotein K (hnRNPK) is closely associated with cancer pro...

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Bibliographic Details
Main Authors: Woo Joo Lee, Chang Hoon Shin, Haein Ji, Seong Dong Jeong, Mi-So Park, Hong-Hee Won, Poonam R. Pandey, Dimitrios Tsitsipatis, Myriam Gorospe, Hyeon Ho Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03575-1