Discontinuous Schedule of Bevacizumab in Colorectal Cancer Induces Accelerated Tumor Growth and Phenotypic Changes

Antiangiogenics administration in colorectal cancer patients seemed promising therapeutic approach. Inspite of early encouraging results, it however gave only modest clinical benefits. When AAG was administered with discontinuous schedule, the disease showed acceleration in certain cases. Though res...

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Bibliographic Details
Main Authors: Selma Becherirat, Fatemeh Valamanesh, Mojgan Karimi, Anne-Marie Faussat, Jean-Marie Launay, Cynthia Pimpie, Amu Therwath, Marc Pocard
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523317304187