Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p′-dde levels in a population-based sample

Objectives: Since the metabolism of the organochlorine pesticide dichlorodiphenyltrichloroethane (DDT) is not fully known in humans, we evaluated if circulating levels of a major breakdown product of DDT, p,p′-DDE, were related to genome-wide genetic and methylation variation in a population-based s...

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Bibliographic Details
Main Authors: Lars Lind, Esther Ng, Erik Ingelsson, Cecilia Lindgren, Samira Salihovic, Bert van Bavel, Anubha Mahajan, Erik Lampa, Andrew P. Morris, P. Monica Lind
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412016307619