Association between polymorphisms of the IKZF3 gene and systemic lupus erythematosus in a Chinese Han population.

Association between polymorphisms of the IKZF3 gene and systemic lupus erythematosus in a Chinese Han population.

OBJECTIVE: It has been reported that IKAROS family of zinc finger 3 (IKZF3)-deficient mice spontaneously develop human systemic lupus erythematosus (SLE)-like phenotypes and produce anti-dsDNA Ab leading to immune complex-mediated glomerulonephritis. Polymorphism of the IKZF3 gene corresponds with t...

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Bibliographic Details
Main Authors: Xinze Cai, Ying Qiao, Cheng Diao, Xiaoxue Xu, Yang Chen, Shuyan Du, Xudong Liu, Nan Liu, Shuang Yu, Dong Chen, Yi Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182708?pdf=render

Internet

http://europepmc.org/articles/PMC4182708?pdf=render

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