TWIST1 Heterodimerization with E12 Requires Coordinated Protein Phosphorylation to Regulate Periostin Expression

TWIST1 Heterodimerization with E12 Requires Coordinated Protein Phosphorylation to Regulate Periostin Expression

Diffuse invasion into adjacent brain matter by glioblastoma (GBM) is largely responsible for their dismal prognosis. Previously, we showed that the TWIST1 (TW) bHLH transcription factor and its regulated gene periostin (<i>POSTN</i>) promote invasive phenotypes of GBM cells. Since TW fun...

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Bibliographic Details
Main Authors: Svetlana A. Mikheeva, Nathan D. Camp, Lei Huang, Antrix Jain, Sung Yun Jung, Naze G. Avci, Mari Tokita, Alejandro Wolf-Yadlin, Jing Zhang, Stephen J. Tapscott, Robert C. Rostomily, Andrei M. Mikheev
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
TWIST1
dimerization
invasion
glioblastoma
periostin
Online Access:https://www.mdpi.com/2072-6694/11/9/1392

Internet

https://www.mdpi.com/2072-6694/11/9/1392

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