Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats

Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats

Abstract Central sensitization plays a pivotal role in the maintenance of chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. This study was designed to examine the role of anterior insular cortex (aIC) in the pathogenesis of hyperalgesia in a ra...

Full description

Bibliographic Details
Main Authors: Yang Bai, Li-Tian Ma, Yan-Bing Chen, Dan Ren, Ying-Biao Chen, Ying-Qi Li, Hong-Ke Sun, Xin-Tong Qiu, Ting Zhang, Ming-Ming Zhang, Xi-Nan Yi, Tao Chen, Hui Li, Bo-Yuan Fan, Yun-Qing Li
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Molecular Brain
Subjects:
Rat
Chronic pancreatitis
Anterior insular cortex
Long-term potentiation
Excitatory synaptic transmission
Hyperalgesia
Online Access:http://link.springer.com/article/10.1186/s13041-019-0497-5

Internet

http://link.springer.com/article/10.1186/s13041-019-0497-5

Similar Items