Extreme Antibiotic Persistence via Heterogeneity-Generating Mutations Targeting Translation

Bacterial persistence is a fascinating phenomenon in which a small subpopulation of bacteria becomes phenotypically tolerant to lethal antibiotic exposure. There is growing evidence that populations of bacteria in chronic clinical infections develop a hyperpersistent phenotype, enabling a substantia...

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Bibliographic Details
Main Authors: Anupama Khare, Saeed Tavazoie
Format: Article
Language:English
Published: American Society for Microbiology 2020-01-01
Series:mSystems
Subjects:
Online Access:https://doi.org/10.1128/mSystems.00847-19