Neutrophil Elastase Facilitates Tumor Cell Intravasation and Early Metastatic Events

Neutrophil Elastase Facilitates Tumor Cell Intravasation and Early Metastatic Events

Summary: Functional roles of neutrophil elastase (NE) have not been examined in distinct steps of the metastatic cascade. NE, delivered to primary tumors as a purified enzyme or within intact neutrophils or neutrophil granule content, enhanced human tumor cell intravasation and subsequent disseminat...

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Bibliographic Details
Main Authors: Elena Deryugina, Alexia Carré, Veronica Ardi, Tomoki Muramatsu, Jonas Schmidt, Christine Pham, James P. Quigley
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Cell Biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309962

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http://www.sciencedirect.com/science/article/pii/S2589004220309962

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