Plasma cholesterol level determines in vivo prion propagation[S]
Transmissible spongiform encephalopathies are fatal neurodegenerative diseases with an urgent need for therapeutic and prophylactic strategies. At the time when the blood-mediated transmission of prions was demonstrated, in vitro studies indicated a high binding affinity of the scrapie prion protein...
Main Authors: | Véronique Perrier, Thibaud Imberdis, Pierre-André Lafon, Marina Cefis, Yunyun Wang, Elisabeth Huetter, Jacques-Damien Arnaud, Teresa Alvarez-Martinez, Naig Le Guern, Guillaume Maquart, Laurent Lagrost, Catherine Desrumaux |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-10-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520335665 |
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