Plasma cholesterol level determines in vivo prion propagation[S]

Plasma cholesterol level determines in vivo prion propagation[S]

Transmissible spongiform encephalopathies are fatal neurodegenerative diseases with an urgent need for therapeutic and prophylactic strategies. At the time when the blood-mediated transmission of prions was demonstrated, in vitro studies indicated a high binding affinity of the scrapie prion protein...

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Bibliographic Details
Main Authors: Véronique Perrier, Thibaud Imberdis, Pierre-André Lafon, Marina Cefis, Yunyun Wang, Elisabeth Huetter, Jacques-Damien Arnaud, Teresa Alvarez-Martinez, Naig Le Guern, Guillaume Maquart, Laurent Lagrost, Catherine Desrumaux
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Journal of Lipid Research
Subjects:
lipid transfer proteins
lipoproteins
neurons
brain
animal models
neurodegenerative diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520335665

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http://www.sciencedirect.com/science/article/pii/S0022227520335665

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