Reprogramming with Small Molecules instead of Exogenous Transcription Factors

Induced pluripotent stem cells (iPSCs) could be employed in the creation of patient-specific stem cells, which could subsequently be used in various basic and clinical applications. However, current iPSC methodologies present significant hidden risks with respect to genetic mutations and abnormal ex...

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Bibliographic Details
Main Authors: Tongxiang Lin, Shouhai Wu
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2015/794632