Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq.
Long noncoding RNAs (lncRNAs) localize in the cell nucleus and influence gene expression through a variety of molecular mechanisms. Chromatin-enriched RNAs (cheRNAs) are a unique class of lncRNAs that are tightly bound to chromatin and putatively function to locally cis-activate gene transcription....
Main Authors: | Xiangying Sun, Zhezhen Wang, Johnathon M Hall, Carlos Perez-Cervantes, Alexander J Ruthenburg, Ivan P Moskowitz, Michael Gribskov, Xinan H Yang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-02-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1007119 |
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