Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq.

Long noncoding RNAs (lncRNAs) localize in the cell nucleus and influence gene expression through a variety of molecular mechanisms. Chromatin-enriched RNAs (cheRNAs) are a unique class of lncRNAs that are tightly bound to chromatin and putatively function to locally cis-activate gene transcription....

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Bibliographic Details
Main Authors: Xiangying Sun, Zhezhen Wang, Johnathon M Hall, Carlos Perez-Cervantes, Alexander J Ruthenburg, Ivan P Moskowitz, Michael Gribskov, Xinan H Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007119