A specific binding site for the prorenin propart peptide Arg-Arg does not occur on human endothelial cells

Introduction. We looked for novel binding sites for the human prorenin ‘decoy peptide’ sometimes called ‘handle region peptide’ on human endothelial cells. Method. The biotinylated peptide biotin-Acp-RIFLKRMPSIR (B-PR), an unlabelled peptide PR1 (RIFLKRMPSIR) and a scrambled peptide scPR1 (SRRMIFPIK...

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Bibliographic Details
Main Authors: Brenda J Leckie, Andrew R Bottrill
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2011-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320310370610