MAR elements and transposons for improved transgene integration and expression.

Reliable and long-term expression of transgenes remain significant challenges for gene therapy and biotechnology applications, especially when antibiotic selection procedures are not applicable. In this context, transposons represent attractive gene transfer vectors because of their ability to promo...

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Bibliographic Details
Main Authors: Déborah Ley, Niamh Harraghy, Valérie Le Fourn, Solenne Bire, Pierre-Alain Girod, Alexandre Regamey, Florence Rouleux-Bonnin, Yves Bigot, Nicolas Mermod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3640020?pdf=render