Contributions of the Hippocampal CA3 Circuitry to Acute Seizures and Hyperexcitability Responses in Mouse Models of Brain Ischemia

Contributions of the Hippocampal CA3 Circuitry to Acute Seizures and Hyperexcitability Responses in Mouse Models of Brain Ischemia

The hippocampal circuitry is widely recognized as susceptible to ischemic injury and seizure generation. However, hippocampal contribution to acute non-convulsive seizures (NCS) in models involving middle cerebral artery occlusion (MCAO) remains to be determined. To address this, we occluded the mid...

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Bibliographic Details
Main Authors: Hongmei Song, Sivakami M. Mylvaganam, Justin Wang, Saeyon M. K. Mylvaganam, Chiping Wu, Peter L. Carlen, James H. Eubanks, Jiachun Feng, Liang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
brain slices
CA3
discharges
EEG
epileptiform
EPSC
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00278/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00278/full

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