Muricholic acids inhibit Clostridium difficile spore germination and growth.

Infections caused by Clostridium difficile have increased steadily over the past several years. While studies on C. difficile virulence and physiology have been hindered, in the past, by lack of genetic approaches and suitable animal models, newly developed technologies and animal models allow these...

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Bibliographic Details
Main Authors: Michael B Francis, Charlotte A Allen, Joseph A Sorg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3767737?pdf=render