Hepatotoxic potential of asarones: In vitro evaluation of hepatotoxicity and quantitative determination in herbal products

Hepatotoxic potential of asarones: In vitro evaluation of hepatotoxicity and quantitative determination in herbal products

α and β asarones are natural constituents of some aromatic plants, especially species of the genus Acorus. In addition to beneficial properties of asarones, genotoxicity and carcinogenicity are also reported. Due to potential toxic effects of β-asarone, a limit of exposure from herbal products of ap...

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Bibliographic Details
Main Authors: Dhavalkumar Narendrabha Patel, Han Kiat eHo, Libei Liesbet Tan, Mui-Mui Belinda Tan, Qian eZhang, Min-Yong eLow, Cheng-Leng eChan, Hwee-Ling eKoh
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Pharmacology
Subjects:
Gas Chromatography-Mass Spectrometry
Hepatotoxicity
Oxidative stress.
herbal medicines
GC-MS analysis
Asarones
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00025/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00025/full

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