Smad-Independent BMP Signaling in Somatic Cells Limits the Size of the Germline Stem Cell Pool

Summary: In developing organisms, proper tuning of the number of stem cells within a niche is critical for the maintenance of adult tissues; however, the involved mechanisms remain largely unclear. Here, we demonstrate that Thickveins (Tkv), a type I bone morphogenetic protein (BMP) receptor, acts i...

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Bibliographic Details
Main Authors: Chen-Yuan Tseng, Yu-Han Su, Shun-Min Yang, Kun-Yang Lin, Chun-Ming Lai, Elham Rastegari, Oyundari Amartuvshin, Yueh Cho, Yu Cai, Hwei-Jan Hsu
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118303138