Functional Haplotype of <i>LIPC</i> Induces Triglyceride-Mediated Suppression of HDL-C Levels According to Genome-Wide Association Studies

Functional Haplotype of <i>LIPC</i> Induces Triglyceride-Mediated Suppression of HDL-C Levels According to Genome-Wide Association Studies

Hepatic lipase (encoded by <i>LIPC</i>) is a glycoprotein in the triacylglycerol lipase family and mainly synthesized in and secreted from the liver. Previous studies demonstrated that hepatic lipase is crucial for reverse cholesterol transport and modulating metabolism and the plasma le...

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Bibliographic Details
Main Authors: Yu-Huang Liao, Leay-Kiaw Er, Semon Wu, Yu-Lin Ko, Ming-Sheng Teng
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
hepatic lipase
genome-wide association study
suppression effect
triglyceride
high-density lipoprotein cholesterol
Online Access:https://www.mdpi.com/2073-4425/12/2/148

Internet

https://www.mdpi.com/2073-4425/12/2/148

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