Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

<p>Abstract</p> <p>Background</p> <p>The cationic lipid Genzyme lipid (GL) 67 is the current "gold-standard" for <it>in vivo </it>lung gene transfer. Here, we assessed, if GL67 mediated uptake of siRNAs and asODNs into airway epithelium <it>i...

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Main Authors: Hu Jim, Chow Yu-Hua, Hyde Stephen C, Gill Deborah R, Smith Rbecca L, Painter Hazel, Somerton Luci, Singh Charanjit, Farley Raymond, Garcia Sara, Kitson Chris, Griesenbach Uta, Gray Mike, Edbrooke Mark, Ogilvie Varrie, MacGregor Gordon, Scheule Ronald K, Cheng Seng H, Caplen Natasha J, Alton Eric WFW
Format: Article
Language:English
Published: BMC 2006-02-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/26

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http://respiratory-research.com/content/7/1/26

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