Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin

Recent successes of adeno-associated virus (AAV)âbased gene therapy have created a demand for large-scale AAV vector manufacturing and purification techniques for use in clinical trials and beyond. During the development of purification protocols for rh.10, hu.37, AAV8, rh.64R1, AAV3B, and AAV9 vect...

Full description

Bibliographic Details
Main Authors: Qiang Wang, Martin Lock, Andrew J Prongay, Mauricio R Alvira, Boris Petkov, James M Wilson
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116300523