Polyphenols and IUGR Pregnancies: Effects of Maternal Hydroxytyrosol Supplementation on Placental Gene Expression and Fetal Antioxidant Status, DNA-Methylation and Phenotype

Polyphenols and IUGR Pregnancies: Effects of Maternal Hydroxytyrosol Supplementation on Placental Gene Expression and Fetal Antioxidant Status, DNA-Methylation and Phenotype

The use of polyphenols is a promising strategy for preventing or alleviating intrauterine growth restriction (IUGR) because polyphenol supplementation increases plasma antioxidant capacity and improves oxidative stress at the feto-placental unit; which are recognized as main issues in IUGR. However,...

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Bibliographic Details
Main Authors: Consolación Garcia-Contreras, Marta Vazquez-Gomez, Alicia Barbero, José Luis Pesantez, Angelo Zinellu, Fiammetta Berlinguer, Pedro Gonzalez-Añover, Jorge Gonzalez, Teresa Encinas, Laura Torres-Rovira, Yolanda Nuñez, Jaime Ballesteros, Miriam Ayuso, Susana Astiz, Beatriz Isabel, Cristina Ovilo, Antonio Gonzalez-Bulnes
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
antioxidants
intrauterine-growth-restriction
pregnancy
swine-model
Online Access:http://www.mdpi.com/1422-0067/20/5/1187

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http://www.mdpi.com/1422-0067/20/5/1187

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