Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins.

Non-structural protein 1 (NS1) is one of the most enigmatic proteins of the Dengue virus (DENV), playing distinct functions in immune evasion, pathogenesis and viral replication. The recently reported crystal structure of DENV NS1 revealed its peculiar three-dimensional fold; however, detailed infor...

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Bibliographic Details
Main Authors: Pietro Scaturro, Mirko Cortese, Laurent Chatel-Chaix, Wolfgang Fischl, Ralf Bartenschlager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005277