Is There a Future for Anti-CD38 Antibody Therapy in Systemic Autoimmune Diseases?

CD38 is a type II glycoprotein highly expressed on plasmablasts, short-lived and long-lived plasma cells, but weakly expressed on other lymphoid cells, myeloid cells and non-hematopoietic cells. This expression pattern makes CD38 an interesting target for a targeted therapy aiming to deplete antibod...

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Bibliographic Details
Main Authors: Devis Benfaremo, Armando Gabrielli
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cells
Subjects:
ssc
sle
Online Access:https://www.mdpi.com/2073-4409/9/1/77