Profile of entrectinib in the treatment of ROS1-positive non-small cell lung cancer: Evidence to date
ROS proto-oncogene 1 (ROS1) encodes a type I integral membrane protein with tyrosine kinase activity and whose activating alterations are involved in the aggressiveness of several tumor types. Fusions involving ROS1 gene are present in 1–2% of lung adenocarcinomas and other solid tumors. Entrectinib...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | Hematology/Oncology and Stem Cell Therapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1658387620301771 |