Heme Oxygenase-1 Inhibits HLA Class I Antibody-Dependent Endothelial Cell Activation.

Antibody-mediated rejection (AMR) is a key limiting factor for long-term graft survival in solid organ transplantation. Human leukocyte antigen (HLA) class I (HLA I) antibodies (Abs) play a major role in the pathogenesis of AMR via their interactions with HLA molecules on vascular endothelial cells...

Full description

Bibliographic Details
Main Authors: Eva Zilian, Hendry Saragih, Vijith Vijayan, Oliver Hiller, Constanca Figueiredo, Abid Aljabri, Rainer Blasczyk, Gregor Theilmeier, Jan Ulrich Becker, Jan Larmann, Stephan Immenschuh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4686182?pdf=render