Role of Plasmodium falciparum Kelch 13 Protein Mutations in P. falciparum Populations from Northeastern Myanmar in Mediating Artemisinin Resistance

Role of Plasmodium falciparum Kelch 13 Protein Mutations in P. falciparum Populations from Northeastern Myanmar in Mediating Artemisinin Resistance

Artemisinin resistance has emerged in Southeast Asia, endangering the substantial progress in malaria elimination worldwide. It is associated with mutations in the PfK13 protein, but how PfK13 mediates artemisinin resistance is not completely understood. Here we used a new antibody against PfK13 to...

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Bibliographic Details
Main Authors: Faiza Amber Siddiqui, Rachasak Boonhok, Mynthia Cabrera, Huguette Gaelle Ngassa Mbenda, Meilian Wang, Hui Min, Xiaoying Liang, Junling Qin, Xiaotong Zhu, Jun Miao, Yaming Cao, Liwang Cui
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mBio
Subjects:
pfk13
plasmodium falciparum
artemisinin resistance
china-myanmar border
mutations
drug resistance
Online Access:https://doi.org/10.1128/mBio.01134-19

Internet

https://doi.org/10.1128/mBio.01134-19

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