Anti-cancer activity of сuraxin CBL0137 on the models of acute leukemia in vitro

Background. Curaxin CBL0137 is a novel non-genotoxic compound with anti-cancer activity based on CBL0137 ability of non-covalent interaction with DNA causing histone chaperone FACT relocation. Anti-cancer activity of this drug was demonstrated previously on the wide panel of solid cancer models in v...

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Main Authors: T. I. Fetisov, K. I. Kirsanov, A. A. Borunova, M. N. Zatsepina, E. A. Lesovaya, T. N. Zabotina, G. A. Belitsky, M. G. Yakubovskaya
Format: Article
Language:Russian
Published: ABV-press 2019-12-01
Series:Uspehi Molekulârnoj Onkologii
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Online Access:https://umo.abvpress.ru/jour/article/view/242