Attempt to Untangle the Prion-Like Misfolding Mechanism for Neurodegenerative Diseases

Attempt to Untangle the Prion-Like Misfolding Mechanism for Neurodegenerative Diseases

The misfolding and aggregation of proteins is the neuropathological hallmark for numerous diseases including Alzheimer’s disease, Parkinson’s disease, and prion diseases. It is believed that misfolded and abnormal β-sheets forms of wild-type proteins are the vectors of t...

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Bibliographic Details
Main Author: Daniela Sarnataro
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
Aβ
aggregation
amyloid
APP
misfolding
prion protein
prion-like
PrP
seeds
tau
Online Access:http://www.mdpi.com/1422-0067/19/10/3081

Internet

http://www.mdpi.com/1422-0067/19/10/3081

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