Long-term leukocyte reconstitution in NSG mice transplanted with human cord blood hematopoietic stem and progenitor cells

Long-term leukocyte reconstitution in NSG mice transplanted with human cord blood hematopoietic stem and progenitor cells

Abstract Background Humanized mice (hu mice) are based on the transplantation of hematopoietic stem and progenitor cells into immunodeficient mice and have become important pre-clinical models for biomedical research. However, data about their hematopoiesis over time are scarce. We therefore charact...

Full description

Bibliographic Details
Main Authors: Annette Audigé, Mary-Aude Rochat, Duo Li, Sandra Ivic, Audrey Fahrny, Christina K. S. Muller, Gustavo Gers-Huber, Renier Myburgh, Simon Bredl, Erika Schlaepfer, Alexandra U. Scherrer, Stefan P. Kuster, Roberto F. Speck
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Immunology
Subjects:
Hematopoiesis
Hematopoietic stem cells
Cord blood stem cell transplantation
Humanized mice
NSG mice
Online Access:http://link.springer.com/article/10.1186/s12865-017-0209-9

Internet

http://link.springer.com/article/10.1186/s12865-017-0209-9

Similar Items