Chronic Lorcaserin Treatment Reverses the NicotineWithdrawal-Induced Disruptions to Behavior and Maturation in Developing Neurons in the Hippocampus of Rats

Chronic Lorcaserin Treatment Reverses the NicotineWithdrawal-Induced Disruptions to Behavior and Maturation in Developing Neurons in the Hippocampus of Rats

Preclinical data have shown that treatment with serotonin (5-HT)<sub>2C</sub> receptor agonists inhibits the behavioral effects of nicotine, including self-administration, reinstatement, and locomotor responses to nicotine. Since the data on the effects of 5-HT<sub>2C</sub> r...

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Bibliographic Details
Main Authors: Magdalena Zaniewska, Agnieszka Nikiforuk, Urszula Głowacka, Sabina Brygider, Julita Wesołowska, Ewa Litwa, Marzena Maćkowiak
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
5-HT<sub>2C</sub> receptor
forced swim test
adult hippocampal neurogenesis
nicotine self-administration
novel object recognition
rat
Online Access:https://www.mdpi.com/1422-0067/22/2/868

Internet

https://www.mdpi.com/1422-0067/22/2/868

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