Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen.

Human strongyloidiasis varies from a chronic but limited infection in normal hosts to hyperinfection in patients treated with corticosteroids or with HTLV-1 co-infection. Regulatory T cells dampen immune responses to infections. How human strongyloidiasis is controlled and how HTLV-1 infection affec...

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Bibliographic Details
Main Authors: Martin Montes, Cesar Sanchez, Kristien Verdonck, Jordan E Lake, Elsa Gonzalez, Giovanni Lopez, Angelica Terashima, Thomas Nolan, Dorothy E Lewis, Eduardo Gotuzzo, A Clinton White
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2686100?pdf=render