In silico investigation of a KCNQ1 mutation associated with short QT syndrome
Abstract Short QT syndrome (SQTS) is a rare condition characterized by abnormally ‘short’ QT intervals on the ECG and increased susceptibility to cardiac arrhythmias and sudden death. This simulation study investigated arrhythmia dynamics in multi-scale human ventricle models associated with the SQT...
Main Authors: | Ismail Adeniran, Dominic G. Whittaker, Aziza El Harchi, Jules C. Hancox, Henggui Zhang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-08367-2 |
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