Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects
<p>Abstract</p> <p>Background</p> <p>Congenital cardiovascular diseases are the most common form of birth defects in humans. A substantial portion of these defects has been associated with inappropriate induction, migration, differentiation and patterning of pluripotent...
Main Authors: | Sucov Henry M, Dudas Marek, Larsson Jonas, Nagy Andre, Wang Jikui, Kaartinen Vesa |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-11-01
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Series: | BMC Developmental Biology |
Online Access: | http://www.biomedcentral.com/1471-213X/6/51 |
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