Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

<p>Abstract</p> <p>Background</p> <p>Congenital cardiovascular diseases are the most common form of birth defects in humans. A substantial portion of these defects has been associated with inappropriate induction, migration, differentiation and patterning of pluripotent...

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Bibliographic Details
Main Authors: Sucov Henry M, Dudas Marek, Larsson Jonas, Nagy Andre, Wang Jikui, Kaartinen Vesa
Format: Article
Language:English
Published: BMC 2006-11-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/6/51