Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils.

Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils.

Neutrophils and eosinophils are important sources of bioactive lipids from the 5- and the 15-lipoxygenase (LO) pathways. Herein, we compared the effectiveness of humans eosinophils and eosinophil-depleted neutrophils to synthesize 15-LO metabolites using a cocktail of different 15-LO substrates as w...

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Bibliographic Details
Main Authors: Anne-Sophie Archambault, Caroline Turcotte, Cyril Martin, Véronique Provost, Marie-Chantal Larose, Catherine Laprise, Jamila Chakir, Élyse Bissonnette, Michel Laviolette, Ynuk Bossé, Nicolas Flamand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6097673?pdf=render

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http://europepmc.org/articles/PMC6097673?pdf=render

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